RO 31-6233
3,4-Bis(3-indolyl)maleimide
CAS: 119139-23-0
Molecular Formula: C20H13N3O2
RO 31-6233 - Names and Identifiers
| Name | 3,4-Bis(3-indolyl)maleimide |
| Synonyms | RO 31-6233 3,4-BIS(3-INDOLYL)MALEIMIDE 3,4-Bis(3-indolyl)maleimide 2,3-BIS(1H-INDOL-3-YL)MALEIMIDE Bisindolylmaleimide IV (Arcyriarubin A) 3,4-Di-1H-indol-3-yl-1H-pyrrole-2,5-dione 1,3-di(1H-indol-2-yl)-1H-pyrrole-2,5-dione 1H-Pyrrole-2,5-dione, 3,4-di-1H-indol-3-yl- 3,4-BIS(3-INDOLYL)MALEIMIDE (ARCYRIARUBIN A). 3-(1H-Indole-3-yl)-4-(1H-indole-3-yl)-1H-pyrrole-2,5-dione |
| CAS | 119139-23-0 |
| InChI | InChI=1/C20H13N3O2/c24-19-11-14(17-9-12-5-1-3-7-15(12)21-17)20(25)23(19)18-10-13-6-2-4-8-16(13)22-18/h1-11,21-22H |
RO 31-6233 - Physico-chemical Properties
| Molecular Formula | C20H13N3O2 |
| Molar Mass | 327.34 |
| Density | 1.486±0.06 g/cm3(Predicted) |
| Melting Point | 161 °C |
| Boling Point | 690.1±55.0 °C(Predicted) |
| Flash Point | 345.638°C |
| Solubility | DMSO: soluble |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Dark red solid |
| Color | dark red |
| pKa | 8.44±0.60(Predicted) |
| Storage Condition | -20°C |
| Refractive Index | 1.829 |
| In vitro study | Bisindolylmaleimide IV (Arcyriarubin A) inhibits PKC with an IC 50 of 0.1 μM in 1 % DMSO, while the IC 50 of 0.55 μM in 10 % DMSO. |
RO 31-6233 - Risk and Safety
| WGK Germany | 3 |
RO 31-6233 - Reference Information
| Biological activity | Bisindolylmaleimide IV (Arcyriarubin A) is a potent protein kinase C (PKC) inhibitor with an IC50 range of 0.1-0.55 μM. Bisindolylmaleimide IV also inhibited PKA (IC50=3.1-11.8 μM). Bisindolylmaleimide IV is a potent inhibitor of human cytomegalovirus (HCMV) replication in cell culture with an IC50 of 0.2 μM. |
| target | PKC 0.1-0.55 μ m (IC 50 ) HCMV 0.2 μ m (IC 50 ) |
| in vitro study | Bisindolylmaleimide IV (Arcyriarubin A) inhibits PKC with an IC 50 of 0.1 μM in 1% DMSO, while the IC 50 of 0.55 μM in 10% DMSO. |
Last Update：2024-04-10 22:29:15
Supplier List
Featured ProductsSpot supply
Product Name: BISINDOLYMALEIMIDE IV Visit Supplier Webpage Request for quotationCAS: 119139-23-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 3,4-Di(1H-indol-3-yl)-1H-pyrrole-2,5-dione Request for quotationCAS: 119139-23-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: BISINDOLYMALEIMIDE IV Visit Supplier Webpage Request for quotationCAS: 119139-23-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple SpecificationsSpot supply
Product Name: Arcyriarubin A Visit Supplier Webpage Request for quotationCAS: 119139-23-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 34-Di-1H-indol-3-yl-1H-pyrrole-25-dione Visit Supplier Webpage Request for quotationCAS: 119139-23-0
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: 3,4-Di-1H-indol-3-yl-1H-pyrrole-2,5-dione Visit Supplier Webpage Request for quotation
CAS: 119139-23-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 119139-23-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Featured ProductsSpot supply
Product Name: BISINDOLYMALEIMIDE IV Visit Supplier Webpage Request for quotationCAS: 119139-23-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 3,4-Di(1H-indol-3-yl)-1H-pyrrole-2,5-dione Request for quotationCAS: 119139-23-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: BISINDOLYMALEIMIDE IV Visit Supplier Webpage Request for quotationCAS: 119139-23-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple SpecificationsSpot supply
Product Name: Arcyriarubin A Visit Supplier Webpage Request for quotationCAS: 119139-23-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 34-Di-1H-indol-3-yl-1H-pyrrole-25-dione Visit Supplier Webpage Request for quotationCAS: 119139-23-0
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: 3,4-Di-1H-indol-3-yl-1H-pyrrole-2,5-dione Visit Supplier Webpage Request for quotation
CAS: 119139-23-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 119139-23-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History